1. Truong Thanh Tung et al., Novel (E)-3-(3-oxo-4-substituted-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-N-hydroxypropenamides as Histone Deacetylase Inhibitors: Design, Synthesis and Bioevaluation, Chemistry & Biodiversity, 2023 (Accepted, 05 April 2023), DOI: https://doi.org/10.1002/cbdv.202201030

2. Truong Thanh Tung et al., Novel (E)-3-(1- substituted-1H-indazol-5-yl)-N-hydroxypropenamides as Histone Deacetylase Inhibitors: Design, Synthesis and Structure-Activity Relationships, New Journal of Chemistry, 2023 (Accepted, 23 Jan 2023), DOI: https://doi.org/10.1039/D2NJ04894A.

3. Truong Thanh Tung et al., Potentiation of drug toxicity through virus latency reversal promotes preferential elimination of HIV infected cells, Advanced Therapeutics, 2022, Accepted (DOI: 10.1002/adtp.202200113) 

4. Truong Thanh Tung*, John Nielsen, Drug discovery and development on Pma1, where we are now? A critical review from 1995 to 2022, ChemMedChem, 2022, Accepted (DOI: 10.1002/cmdc.202200356).

5. Luong Xuan Huy, Hai Phuong Bui, Truong Thanh Tung*, Application of the all-hydrocarbon stapling technique in the design of membrane-active peptides" Journal of Medicinal Chemistry, 2022, Accepted.

6. Truong Thanh Tung et al. Design, Synthesis and Evaluation of Novel 2-Oxoindoline-based Acetohydrazides as Antitumor Agents, Scientific Reports, 2022, accepted.

7. Do Thi Mai Dung, Eun Jae Park, Duong Tien Anh, Pham-The Hai, Le Quang Bao, A Young Ji, Jong Soon Kang, Truong Thanh Tung, Sang-Bae Han* and Nguyen-Hai Nam*, Design, Synthesis and Evaluation of Novel (E)-N'-((1-(4-chlorobenzyl)-1H-indol-3-yl)methylene)-2-(4-oxoquinazolin-3(4H)-yl)acetohydrazides as Antitumor Agents, Anti-Cancer Agents in Medicinal Chemistry, 2022, DOI: 10.2174/1871520622666220118154914

8. Huy Xuan Luong*, Hoa Doan Ngan , Hai Bui Thi Phuong , Thang Nguyen Quoc, Truong Thanh Tung*, Multiple roles of ribosomal antimicrobial peptides in tackling global antimicrobial resistance, Royal Society open science, 9,1, 2022.

9. Truong Thanh Tung et. al, Amide bond formation in aqueous solution: direct coupling of metal carboxylate salts with ammonium salts at room temperature, Org. Biomol. Chem., 2021, Advance Article.

10. Do Thi Mai Dung, Eun Jae Park, Duong Tien Anh, Pham-The Hai, Le Dang Huy, Hye Won Jun,  Joo-Hee Kwon, A Young Ji, Jong Soon Kang, Truong Thanh Tung*, Phan Thi Phuong Dung,  Sang-Bae Han, Nguyen-Hai Nam, Design, Synthesis and Evaluation of Novel (E)-N'-(3-Allyl-2-hydroxy)benzylidene-2-(4-oxoquinazolin-3(4H)-yl)acetohydrazides as Antitumor Agents". Archiv der Pharmazie, 2021, Accepted.

11. Truong Thanh Tung*, Huy Luong XuanHuy Luong Xuan, New Journal of Chemistry, 2021, 10.1039/D1NJ04436B, in press, 

12. Truong Thanh Tung*, Thang Nguyen Quoc. 2-Difluoromethylpyridine as a bioisosteric replacement of pyridine-N-oxide: the case of quorum sensing inhibitors. RSC Med. Chem. (Medchemcomm), 2021, Accepted. (invited as cover picture)

13. Tung Truong Thanh*,  Huy Luong Xuan,  Thang Nguyen Quoc, Benzo[d]thiazole-2-thiol bearing 2-oxo-2-substituted-phenylethan-1-yl as potent selective lasB quorum sensing inhibitors of Gram-negative bacteria. RSC Advances, 2021, inpress

14. Truong Thanh Tung*, Thang Nguyen Quoc, Discovery of novel β-turn mimetic-based peptides as novel quorum sensing inhibitors of gram-negative bacteria, Bioorganic & Medicinal Chemistry Letters, 2021, In press, https://doi.org/10.1016/j.bmcl.2021.128170

15. Huy L Xuan, Tam D Duc, Anh M Thuy, Phuong M Chau, Truong T Tung*. Chemical approaches in the development of natural nontoxic peptide Polybia-MP1 as a potential dual antimicrobial and antitumor agent. Amino Acids, doi.org/10.1007/s00726-021-02995-9

16. Novel 4-Oxoquinazoline-Based N -Hydroxypropenamides as Histone Deacetylase Inhibitors: Design, Synthesis, and Biological Evaluation. ACS Omega, DOI: 10.1021/acsomega.0c05870, In print.

17. Truong Thanh Tung*, Luong Xuan Huy, Metal-free synthesis of 2-mercaptobenzothiazoles and 6-(4-substituted-1H-1,2,3-triazol-1-yl)-2-mercaptobenzothiazoles via microwave-assisted synthesis pathway. Synthetic Communications, 2020. (doi.org/10.1080/00397911.2020.1761984)

18. Truong Thanh Tung* et al. Comparison between three techniques for determining glomerular filtration rates: 99mTc - DTPA renography, double plasma sampling method and single plasma sampling method in Vietnamese patients. Indian Journal of Nuclear Medicine,  inpress.

19. Tung Truong Thanh*, Thang Nguyen Quoc, Huy Luong Xuan, Fusaric acid and derivatives as novel antimicrobial agents, Medicinal Chemistry Research (2020), in press.

20. Huy Xuan Luong, Tung Truong Thanh, Tuan Hiep Tran, Antimicrobial peptides – Advances in development of therapeutic applications, Life Sciences, doi.org/10.1016/j.lfs.2020.118407

21. Duong Tien Anh, Pham-The Hai, Do Thi Mai Dung, Phan Thi Phuong Dung, Le-Thi-Thu Huong, Eun Jae Park, Hye Won Jun, Jong Soon Kang, Joo-Hee Kwon, Truong Thanh Tung*, Sang-Bae Han, Nguyen-Hai Nam, Design, synthesis and evaluation of novel indirubin-based N-hydroxybenzamides, N-hydroxypropenamides and N-hydroxyheptanamides as histone deacetylase inhibitors and antitumor agents, Bioorganic & Medicinal Chemistry Letters (2020), https://doi.org/10.1016/j.bmcl.2020.127537

22. Le Cong Huan , Duong Tien Anh , Pham-The Hai , Lai Duc Anh , Eun Jae Park , A Young Ji , Jong Soon Kang , Do Thi Mai Dung , Dao Thi Kim Oanh , Truong Thanh Tung , Dinh Thi Thanh Hai ,Sang-Bae Han & Nguyen-Hai Nam, Design, synthesis, and evaluation of novel N'-substituted-1-(4-chlorobenzyl)-1H-indol-3-carbohydrazides as antitumor agents. Journal of Enzyme Inhibition and Medicinal Chemistry (2020), https://doi.org/10.1080/14756366.2020.1816997

Selected publications

23. Truong Thanh Tung, Trong Tuan Dao, Marta Grifell Junyent, Michael Broberg Palmgren, Thomas Günther-Pomorski, Anja Thoe Fuglsang, Søren Brøgger Christensen, John Nielsen. Brick-by-brick, a Lego-inspired drug design: unveiling of the novel class of benzo[d]thiazole containing a 3,4-dihydroxyphenyl moiety as plasma membrane H+-ATPase inhibitors. ChemMedChem, 2018, 13(1), 37–47 (IF 3.225).

*Selected as cover picture (DOI: 10.1002/cmdc.201700808)

24. John Nielsen, Søren Brøgger Christensen, Truong Thanh Tung. Difluoroacetic Acid as a New Reagent for Direct C–H Difluoromethylation of Heteroaromatic Compounds – Scope, Limitations and Perspectives. (Highlight), Synform, 2018, A193–A196. DOI: 10.1055/s-0037-1609808.

25. Truong Thanh Tung, Søren Brøgger Christensen and John Nielsen. Palladium/Silver-Co-catalyzed C3-Selective direct difluoromethylation of heteroaromatic compounds. Manuscript in preparation.

26. Truong Thanh Tung, Søren Brøgger Christensen and John Nielsen. Difluoroacetic Acid as a New Reagent for Direct C-H Difluoromethylation of Heteroaromatic Compounds. Chemistry - A European Journal, 2017, 23, 18125 –18128 (IF 5.317).

*Hot paper

*Selected as cover picture (DOI: 10.1002/chem.201704732)

27. Ahmed R. Hassan, Salah M. El-kousy, Sayed A. El-Toumy, Karla Frydenvang, Truong Thanh Tung, Jesper Olesen, John Nielsen, Søren Brøgger Christensend. Metformin an anthropogenic contamination in Seidlitzia rosmarinus. Journal of Natural Product, 80, 10, 2830-2834. (IF 3.281)

28. Truong Thanh Tung, Tim Holm Jakobsen, Trong Tuan Dao, Anja Thoe Fuglsang, Michael Givskovb, Søren Brøgger Christensen, John Nielsen. Fusaric acid and analogues as gram-negative bacterial quorum sensing inhibitors. European Journal of Medicinal Chemistry, 2016, 126, 1011-1020. (IF 4.5)

29. Trong Tuan Dao, Pankaj Sehgal, Truong Thanh Tung, Jesper Vuust Møller, John Nielsen, Michael Palmgren, Søren Brøgger Christensen, Anja Thoe Fuglsang. Demethoxycurcumin Is A Potent Inhibitor of P-Type ATPases from Diverse Kingdoms of Life. PLoS One, 2016, 11(9):e0163260. (IF 3.2)

30. Chanwoo Kim, Jinjoo Jung, Truong Thanh Tung and Seung Bum Park. β-Turn mimetic-based stabilizers of protein–protein interactions for the study of the non-canonical roles of leucyl-tRNA synthetase. Chemical Science, 2016, 7, 2753-2761. (IF 9.14)

31. Heejun Kim, Truong Thanh Tung, and Seung Bum Park. Privileged Substructure-Based Diversity-Oriented Synthesis Pathway for Diverse Pyrimidine-Embedded Polyheterocycles, Organic letters, 2013, 15 (22), pp 5814–5817. (IF 6.579)

32. Truong Thanh Tung, Dao Thi Kim Oanh, Phan Thi Phuong Dung, Van Thi My Hue, Sang Ho Park, Byung Woo Han, Youngsoo Kim, Jin-Tae Hong, Sang-Bae Han and Nguyen-Hai Nam. New Benzothiazole/thiazole-Containing Hydroxamic Acids as Potent Histone Deacetylase Inhibitors and Antitumor Agents, Med Chem. 2013, 9(8),1051-7, [PMID: 23521008] (Undergraduate publication). (IF 2.331)

Domestic Publications

1. Truong Thanh Tung, Nguyen Quoc Thang, Tổng hợp, thử kết quả hoạt tính của một số dẫn chất mang nhóm CF2H lên hoạt động của NAChRs trên thần kinh trung ương và xác định các chất chứng âm mới, Tạp chí Dược Học, 2021.

2. Bùi Thị Phương Hải, Đinh Thị Ngọc Mai, Đoàn Ngân Hoa, Nguyễn Hồng Minh, Trương Thanh Tùng, Lương Xuân Huy, Tổng hợp và đánh giá sơ bộ tác dụng kép kháng khuẩn - kháng nấm của peptid tự nhiên Polybia-MP1, Tạp chí Dược Học, 2021.

3. Truong Thanh Tung, Nguyen Quoc Thang, Bước đầu nghiên cứu tổng hợp dẫn chất mới của monometyl auristatin F hướng chống ung thư, Tạp chí Nghiên cứu Dược & Thông tin thuốc, 2022.

CONFERENCE PAPERS AND INVITED SPEAKER

1. Truong Thanh Tung. “LEGO®-inspired drug design and the discovery of novel C-H functionalization difluoromethylation reaction for drug discovery”. Invited Lecture at Danish Chemical Society’s annual meeting in Odense on June 15 2017.

2. Truong Thanh Tung and John Nielsen. LEGO®-inspired drug design: Discovery of novel fungal Plasma membrane H+-ATPase (Pma1) inhibitors from small molecule libraries: An introduction of HFSA-SBS_DOS-RD strategy in drug discovery. Oral presentation at 253rd American Chemical Society (ACS) National Meeting in San Francisco, California, April 2-6, 2017.

3. Truong Thanh Tung and John Nielsen. Perturbing dissimilar biomolecular targets from natural product scaffolds and focused chemical decoration. Poster at 253rd ACS National Meeting in San Francisco, California, April 2-6, 2017.

4. Chanwoo Kim, Jinjoo Jung, Truong Thanh Tung, Seung Bum Park. Design, Synthesis and Construction of a β-Turn Mimetic Library Targeting Protein-Protein Interactions. 2015 IUPAC 48th General Assembly and 45th World Chemistry Congress (IUPAC-2015)

5. Heejun Kim, Truong Thanh Tung, Seung Bum Park. Development of pyrimidine embedded DOS pathway. 14th Tetrahedron Symposium, Vienna, Austria, 2013.

6. Heejun Kim, Truong Thanh Tung, Seung Bum Park. Privileged Substructure-Based Diversity-Oriented Synthesis Pathway for Diverse Pyrimidine-Embedded Polyheterocycles, 3rd CAMPUS Asia Symposium, 07/11/2013, Seoul National University.

7. Truong Thanh Tung, Oanh Dao Thi Kim, Nam Nguyen Hai. Design, synthesis and evaluation some new compounds potential histone deacetylase inhibitors. Oral presentation at Youth on Med.& Phar. Hanoi University of Pharmacy bulletin, (6)2012.

PROFESSIONAL SERVICES

Editor for:

BMC Chemistry (BioMed Central)

 Frontiers in chemistry

Plos ONE

BMC Research Notes

EAB for BMC & BMCL

Reviewer for the following journals: 

Scientific reports (Nature Publishing AG)

Communications Chemistry (Nature Publishing AG); 

Medicinal Chemistry Research

Bulletin of the Korean Chemical Society

BMC Chemistry (BioMed Central)

Frontiers in chemistry

Marine Drugs 

Molecules (MDPI)..........

PATENTS

Nguyen Hai Nam; Van Thi My Hue; Dao Thi Kim Oanh; Truong Thanh Tung; Han, Sang-Bae; Kim, Young Soo; Hong, Jin Tae: “Novel Hydroxamic Acids Having Histone Deacetylase Inhibiting Activity and Anti-Cancer Composition Comprising the Same As An Active Ingredient”, 2012. (120621-PN120251-1020120066831).

TEACHING AND STUDENTS:

MSc. Students (co-supervised with Prof. John Nielsen):

- Mujtaba Kamal A. Hassan (University of Copenhagen, graduated in 2016-2017, now PhD student at Lund University)

- Tobias (University of Copenhagen, graduated in 2016-2017)

- Jacob Sørensen (University of Copenhagen, graduated in 2019-2020)

- Peter Hansen (University of Copenhagen, graduated in 2019-2020)

Undergraduate course:

- Natural products and Pharmacognosy, University of Copenhagen 2016-2017